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Newv2.4 · Mar 28, 2025
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DAH in Post-Transplant Patients
Clinical Scenario
A 45-year-old patient presents with bilateral ground-glass opacities post stem cell transplant
Teaching Pearl
DAH in post-transplant patients — think engraftment syndrome if within 30 days. BAL is key for diagnosis.
What's Inside
Aligned with PCCM fellowship curriculumPCCM Subspecialties
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DetailsAll content mapped to PCCM fellowship curriculum and weighted by ABIM exam blueprint.
Featured Content
Browse LibraryA Randomized Trial of Protocol-Based Care for Early Septic Shock (ProCESS)
Protocolized EGDT (with ScvO₂ monitoring, CVP targets, and blood transfusions) is not superior to usual care in septic shock. The key elements that matter are: early recognition, prompt antibiotics, and adequate resuscitation — not the specific protocol endpoints.
Prednisone, Azathioprine, and N-Acetylcysteine for Pulmonary Fibrosis (PANTHER-IPF)
Triple therapy (prednisone + azathioprine + NAC) is HARMFUL in IPF and must not be used. IPF is NOT an inflammatory disease — it is a fibrotic disease. This trial fundamentally changed the understanding of IPF pathophysiology.
A Phase 3 Trial of Pirfenidone in Patients with Idiopathic Pulmonary Fibrosis (ASCEND)
Pirfenidone significantly slows FVC decline in IPF and is FDA-approved for this indication. It is one of two antifibrotic agents (along with nintedanib) that are standard of care for IPF.
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